High-fidelity in vivo replication of DNA base shape mimics without Watson–Crick hydrogen bonds

We report studies testing the importance of Watson–Crick hydrogen bonding, base-pair geometry, and steric effects during DNA replication in living bacterial cells. Nonpolar DNA base shape mimics of thymine and adenine (abbreviated F and Q, respectively) were introduced into Escherichia coli by inser...

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izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Delaney, James C., Henderson, Paul T., Helquist, Sandra A., Morales, Juan C., Essigmann, John M., Kool, Eric T.
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 2003
Teme:	Biological Sciences
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153579/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12676985/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0837277100
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