3β-Acetoxyandrost-1,5-diene-17-ethylene ketal functions as a potent antiandrogen with marginal agonist activity

The majority of available antiandrogens have been reported to possess agonist activity to induce prostate-specific antigen, which might result in antiandrogen withdrawal syndrome. Here we report the identification of 3β-acetoxyandrost-1,5-diene-17-ethylene ketal (ADEK) from dehydroepiandrosterone me...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Miyamoto, Hiroshi, Marwah, Padma, Marwah, Ashok, Lardy, Henry, Chang, Chawnshang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2003
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153574/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12672951/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0831001100
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