3β-Acetoxyandrost-1,5-diene-17-ethylene ketal functions as a potent antiandrogen with marginal agonist activity

The majority of available antiandrogens have been reported to possess agonist activity to induce prostate-specific antigen, which might result in antiandrogen withdrawal syndrome. Here we report the identification of 3β-acetoxyandrost-1,5-diene-17-ethylene ketal (ADEK) from dehydroepiandrosterone me...

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Detalles Bibliográficos
Main Authors: Miyamoto, Hiroshi, Marwah, Padma, Marwah, Ashok, Lardy, Henry, Chang, Chawnshang
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC153574/
https://ncbi.nlm.nih.gov/pubmed/12672951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0831001100
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