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The use of a physiologically based pharmacokinetic model to evaluate deconvolution measurements of systemic absorption
BACKGROUND: An unknown input function can be determined by deconvolution using the systemic bolus input function (r) determined using an experimental input of duration ranging from a few seconds to many minutes. The quantitative relation between the duration of the input and the accuracy of r is unk...
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153531/ https://ncbi.nlm.nih.gov/pubmed/12659643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-3-1 |
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