Cord blood B cells are mature in their capacity to switch to IgE-producing cells in response to interleukin-4 in vitro.

Neonatal B cells have been considered immature because of their impaired capacity to produce immunoglobulins in response to polyclonal activators in vitro. Here we demonstrate that cord blood mononuclear cells (MNC) produce normal levels of IgE in vitro when cultured in the presence of interleukin-4...

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Autores principales: Pastorelli, G, Rousset, F, Pène, J, Peronne, C, Roncarolo, M G, Tovo, P A, de Vries, J E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1535178/
https://ncbi.nlm.nih.gov/pubmed/2119917
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