Interleukin-4 suppresses immunoglobulin production by peripheral blood lymphocytes of patients with common variable immunodeficiency (CVI) induced by supernatants of T cell clones.

Supernatants of both CD4+ and CD8+ alloreactive T cell clones induced IgM, IgG and IgA synthesis by peripheral blood lymphocytes (PBL) of healthy donors in vitro. These supernatants were also tested on their capacity to induce immunoglobulin production by PBL of four patients with CVI and one patien...

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Hlavní autoři: Pastorelli, G, Roncarolo, M G, Touraine, J L, Rousset, F, Pene, J, de Vries, J E
Médium: Artigo
Jazyk:Inglês
Vydáno: 1989
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534808/
https://ncbi.nlm.nih.gov/pubmed/2575470
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