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Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures

Although it has been established that IL-4 enhances both IgG1 and IgE secretion in LPS-stimulated B cell cultures, these studies failed to determine whether IL-4 preferentially induces isotype switching or preferentially allows for the maturation of precommitted precursor cells. To distinguish betwe...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1988
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189023/
https://ncbi.nlm.nih.gov/pubmed/3049907
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