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Interleukin 5 (IL-5) provides a signal that is required in addition to IL-4 for isotype switching to immunoglobulin (Ig) G1 and IgE

We have examined the contributions of Interleukin 4 (IL-4), IL-5, and other stimuli to the expression of Immunoglobulin G1 (IgG1) and IgE in murine B lymphoblasts activated with anti-Ig. The combination of IL-4 and -5 induced B lymphoblasts to proliferate and to secrete IgM and IgG1. However, an add...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1992
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2119169/
https://ncbi.nlm.nih.gov/pubmed/1552290
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