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The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1(–/–) mice
Neurofibromatosis type I (NF1; also known as von Recklinghausen’s disease) is a common autosomal-dominant condition primarily affecting neural crest–derived tissues. The disease gene, NF1, encodes neurofibromin, a protein of over 2,800 amino acids that contains a 216–amino acid domain with Ras–GTPas...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1533876/ https://ncbi.nlm.nih.gov/pubmed/16906226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28341 |
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