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In Vitro and In Vivo Activities of AM-112, a Novel Oxapenem
AM-112 [(1′R,5R,6R)-3-(4-amino-1,1-dimethyl-butyl)-6-(1′-hydroxyethyl)oxapenem-3-carboxylate] is a novel oxapenem compound which possesses potent β-lactamase-inhibitory properties. Fifty-percent inhibitory concentrations (IC(50)s) of AM-112 for class A enzymes were between 0.16 and 2.24 μM for three...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC153311/ https://ncbi.nlm.nih.gov/pubmed/12709336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.5.1652-1657.2003 |
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