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In Vitro Activities of Novel Oxapenems, Alone and in Combination with Ceftazidime, against Gram-Positive and Gram-Negative Organisms

Four novel oxapenem compounds (i.e., AM-112, AM-113, AM-114, and AM-115) were investigated for their β-lactamase inhibitory activity against a panel of isolated class A, C, and D enzymes, which included expanded-spectrum β-lactamase enzymes (ESBLs). The oxapenems were potent β-lactamase inhibitors....

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Detalhes bibliográficos
Main Authors: Jamieson, Conor E., Lambert, Peter A., Simpson, Iain N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166081/
https://ncbi.nlm.nih.gov/pubmed/12878527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2615-2618.2003
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