In Vitro Activities of Novel Oxapenems, Alone and in Combination with Ceftazidime, against Gram-Positive and Gram-Negative Organisms

Four novel oxapenem compounds (i.e., AM-112, AM-113, AM-114, and AM-115) were investigated for their β-lactamase inhibitory activity against a panel of isolated class A, C, and D enzymes, which included expanded-spectrum β-lactamase enzymes (ESBLs). The oxapenems were potent β-lactamase inhibitors....

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Jamieson, Conor E., Lambert, Peter A., Simpson, Iain N.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2003
Assuntos:	Susceptibility
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166081/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12878527/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.8.2615-2618.2003
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