Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian Cells

The hypoxic tumor microenvironment has been shown to contribute to genetic instability. As one possible mechanism for this effect, we report that expression of the DNA mismatch repair (MMR) gene Mlh1 is specifically reduced in mammalian cells under hypoxia, whereas expression of other MMR genes, inc...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Mihaylova, Valia T., Bindra, Ranjit S., Yuan, Jianling, Campisi, Denise, Narayanan, Latha, Jensen, Ryan, Giordano, Frank, Johnson, Randall S., Rockwell, Sara, Glazer, Peter M.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2003
Fag:	DNA Dynamics and Chromosome Structure
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153206/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12697826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.9.3265-3273.2003
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