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Rev1 is essential for DNA damage tolerance and non-templated immunoglobulin gene mutation in a vertebrate cell line

The majority of DNA damage-induced mutagenesis in the yeast Saccharomyces cerevisiae arises as a result of translesion replication. This process is critically dependent on the deoxycytidyl transferase Rev1p, which forms a complex with the subunits of DNA polymerase ζ, Rev3p and Rev7p. To examine the...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Simpson, Laura J., Sale, Julian E.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152905/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12660171/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg161
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