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Rev1 is essential for DNA damage tolerance and non-templated immunoglobulin gene mutation in a vertebrate cell line

The majority of DNA damage-induced mutagenesis in the yeast Saccharomyces cerevisiae arises as a result of translesion replication. This process is critically dependent on the deoxycytidyl transferase Rev1p, which forms a complex with the subunits of DNA polymerase ζ, Rev3p and Rev7p. To examine the...

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Detalhes bibliográficos
Main Authors: Simpson, Laura J., Sale, Julian E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152905/
https://ncbi.nlm.nih.gov/pubmed/12660171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg161
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