Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint

All eukaryotes respond to DNA damage by modulation of diverse cellular processes to preserve genomic integrity and ensure survival. Here we identify mammalian Tousled like kinases (Tlks) as a novel target of the DNA damage checkpoint. During S-phase progression, when Tlks are maximally active, gener...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Groth, Anja, Lukas, Jiri, Nigg, Erich A., Silljé, Herman H.W., Wernstedt, Christer, Bartek, Jiri, Hansen, Klaus
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2003
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12660173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg151
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