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Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication

Budding yeast Mps1p kinase has been implicated in both the duplication of microtubule-organizing centers and the spindle assembly checkpoint. Here we show that hMps1, the human homolog of yeast Mps1p, is a cell cycle-regulated kinase with maximal activity during M phase. hMps1 localizes to kinetocho...

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Bibliografski detalji
Glavni autori: Stucke, Volker M., Silljé, Herman H.W., Arnaud, Lionel, Nigg, Erich A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC125937/
https://ncbi.nlm.nih.gov/pubmed/11927556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1723
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