Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication
Budding yeast Mps1p kinase has been implicated in both the duplication of microtubule-organizing centers and the spindle assembly checkpoint. Here we show that hMps1, the human homolog of yeast Mps1p, is a cell cycle-regulated kinase with maximal activity during M phase. hMps1 localizes to kinetocho...
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| Vydáno v: | EMBO J |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125937/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11927556/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.7.1723 |
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