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Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication
Budding yeast Mps1p kinase has been implicated in both the duplication of microtubule-organizing centers and the spindle assembly checkpoint. Here we show that hMps1, the human homolog of yeast Mps1p, is a cell cycle-regulated kinase with maximal activity during M phase. hMps1 localizes to kinetocho...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125937/ https://ncbi.nlm.nih.gov/pubmed/11927556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1723 |
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