Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication

Budding yeast Mps1p kinase has been implicated in both the duplication of microtubule-organizing centers and the spindle assembly checkpoint. Here we show that hMps1, the human homolog of yeast Mps1p, is a cell cycle-regulated kinase with maximal activity during M phase. hMps1 localizes to kinetocho...

ver descrição completa

Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Stucke, Volker M., Silljé, Herman H.W., Arnaud, Lionel, Nigg, Erich A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2002
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125937/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11927556/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.7.1723
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!