Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint

All eukaryotes respond to DNA damage by modulation of diverse cellular processes to preserve genomic integrity and ensure survival. Here we identify mammalian Tousled like kinases (Tlks) as a novel target of the DNA damage checkpoint. During S-phase progression, when Tlks are maximally active, gener...

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Dades bibliogràfiques

Publicat a:	EMBO J
Autors principals:	Groth, Anja, Lukas, Jiri, Nigg, Erich A., Silljé, Herman H.W., Wernstedt, Christer, Bartek, Jiri, Hansen, Klaus
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Publishing Group 2003
Matèries:	Articles
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152895/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12660173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg151
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