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Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint
All eukaryotes respond to DNA damage by modulation of diverse cellular processes to preserve genomic integrity and ensure survival. Here we identify mammalian Tousled like kinases (Tlks) as a novel target of the DNA damage checkpoint. During S-phase progression, when Tlks are maximally active, gener...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152895/ https://ncbi.nlm.nih.gov/pubmed/12660173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg151 |
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