Dihydropyrimidine amidohydrolases and dihydroorotases share the same origin and several enzymatic properties

Slime mold, plant and insect dihydropyrimidine amidohydrolases (DHPases, EC 3.5.2.2), which catalyze the second step of pyrimidine and several anti-cancer drug degradations, were cloned and shown to functionally replace a defective DHPase enzyme in the yeast Saccharomyces kluyveri. The yeast and sli...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Principais autores:	Gojkovic, Zoran, Rislund, Lise, Andersen, Birgit, Sandrini, Michael P. B., Cook, Paul F., Schnackerz, Klaus D., Piškur, Jure
Formato:	Artigo
Idioma:	Inglês
Publicado:	Oxford University Press 2003
Assuntos:	Articles
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152861/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12626710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg258
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