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Construction and purification of site-specifically modified DNA templates for transcription assays

Chemical and physical agents can alter the structure of DNA by modifying the bases and the phosphate–sugar backbone, consequently compromising both replication and transcription. During transcription elongation, RNA polymerase complexes can stall at a damaged site in DNA and mark the lesion for repa...

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Autori principali: Perlow, Rebecca A., Schinecker, Thomas M., Kim, Se Jun, Geacintov, Nicholas E., Scicchitano, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC152825/
https://ncbi.nlm.nih.gov/pubmed/12655028
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