Conditional gene expression by controlling translation with tetracycline-binding aptamers

We present a conditional gene expression system in Saccharomyces cerevisiae which exploits direct RNA–metabolite interactions as a mechanism of genetic control. We inserted preselected tetracycline (tc) binding aptamers into the 5′-UTR of a GFP encoding mRNA. While aptamer insertion generally reduce...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Suess, Beatrix, Hanson, Shane, Berens, Christian, Fink, Barbara, Schroeder, Renée, Hillen, Wolfgang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2003
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC152801/
https://ncbi.nlm.nih.gov/pubmed/12655001
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk