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TGF β-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7
Cartilage damage in osteoarthritis (OA) is considered an imbalance between catabolic and anabolic factors, favoring the catabolic side. We assessed whether adenoviral overexpression of transforming growth factor-β (TGFβ) enhanced cartilage repair and whether TGFβ-induced fibrosis was blocked by loca...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1526625/ https://ncbi.nlm.nih.gov/pubmed/16584530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1931 |
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