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Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro

Eg5, a member of the kinesin superfamily of microtubule-based motors, is essential for bipolar spindle assembly and maintenance during mitosis, yet little is known about the mechanisms by which it accomplishes these tasks. Here, we used an automated optical trapping apparatus in conjunction with a n...

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書誌詳細
主要な著者: Valentine, Megan T., Fordyce, Polly M., Krzysiak, Troy C., Gilbert, Susan P., Block, Steven M.
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523314/
https://ncbi.nlm.nih.gov/pubmed/16604065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1394
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