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Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro
Eg5, a member of the kinesin superfamily of microtubule-based motors, is essential for bipolar spindle assembly and maintenance during mitosis, yet little is known about the mechanisms by which it accomplishes these tasks. Here, we used an automated optical trapping apparatus in conjunction with a n...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1523314/ https://ncbi.nlm.nih.gov/pubmed/16604065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1394 |
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