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An unexpected requirement for brain-type sodium channels for control of heart rate in the mouse sinoatrial node
Voltage-gated Na(+) channels are composed of pore-forming α and auxiliary β subunits. The majority of Na(+) channels in the heart contain tetrodotoxin (TTX)-insensitive Na(v)1.5 α subunits, but TTX-sensitive brain-type Na(+) channel α subunits are present and functionally important in the transverse...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152323/ https://ncbi.nlm.nih.gov/pubmed/12631690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2627986100 |
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