Translational Compensation of a Frameshift Mutation Affecting Herpes Simplex Virus Thymidine Kinase Is Sufficient To Permit Reactivation from Latency

Herpes simplex virus thymidine kinase is important for reactivation of virus from its latent state and is a target for the antiviral drug acyclovir. Most acyclovir-resistant isolates have mutations in the thymidine kinase gene; however, how these mutations confer clinically relevant resistance is un...

Повний опис

Бібліографічні деталі

Опубліковано в::	J Virol
Автори:	Griffiths, Anthony, Chen, Shun-Hua, Horsburgh, Brian C., Coen, Donald M.
Формат:	Artigo
Мова:	Inglês
Опубліковано:	American Society for Microbiology (ASM) 2003
Предмети:	Vaccines and Antiviral Agents
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152167/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12663777/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.8.4703-4709.2003
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!