Interleukin-18 Impairs the Pulmonary Host Response to Pseudomonas aeruginosa

Interleukin-18 (IL-18) is a potent cytokine with many different proinflammatory activities. To study the role of IL-18 in the pathogenesis of Pseudomonas pneumonia, IL-18-deficient (IL-18(−/−)) and wild-type mice were intranasally inoculated with Pseudomonas aeruginosa. IL-18 deficiency was associat...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Schultz, Marc J., Knapp, Sylvia, Florquin, Sandrine, Pater, Jennie, Takeda, Kiyoshi, Akira, Shizuo, van der Poll, Tom
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Host Response and Inflammation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152024/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654774/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.4.1630-1634.2003
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