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Interleukin-18 Impairs the Pulmonary Host Response to Pseudomonas aeruginosa
Interleukin-18 (IL-18) is a potent cytokine with many different proinflammatory activities. To study the role of IL-18 in the pathogenesis of Pseudomonas pneumonia, IL-18-deficient (IL-18(−/−)) and wild-type mice were intranasally inoculated with Pseudomonas aeruginosa. IL-18 deficiency was associat...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152024/ https://ncbi.nlm.nih.gov/pubmed/12654774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.1630-1634.2003 |
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