Insulin signaling is required for insulin’s direct and indirect action on hepatic glucose production
We and others have suggested that insulin predominantly acts indirectly to inhibit hepatic glucose production (HGP) via suppression of gluconeogenic precursors, FFAs, and glucagon. To test that hypothesis, we performed high-dose hyperinsulinemic-euglycemic clamps using [3-(3)H]-glucose in liver-spec...
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| Опубликовано в:: | J Clin Invest |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151923/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12588884/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16426 |
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