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Unique risk factors for insertional mutagenesis in a mouse model of XSCID gene therapy
Although gene therapy can cure patients with severe combined immunodeficiency (SCID) syndromes, the clinical occurrence of T cell malignancies due to insertional mutagenesis has raised concerns about the safety of gene therapy. Several key questions have remained unanswered: (i) are there unique ris...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1518804/ https://ncbi.nlm.nih.gov/pubmed/16864781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603635103 |
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