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Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting

Decay-accelerating factor (DAF) is a glycosylphosphatidylinositol (GPI)-anchored membrane protein that inhibits both the classical and the alternative pathways of complement activation. DAF has been studied extensively in humans under two clinical settings: when absent from the erythrocytes of parox...

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Bibliografiske detaljer
Main Authors: Sun, Xiujun, Funk, Colin D., Deng, Chengjun, Sahu, Arvind, Lambris, John D., Song, Wen-Chao
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC15187/
https://ncbi.nlm.nih.gov/pubmed/9892684
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