Essential role for proteinase-activated receptor-2 in arthritis

Using physiological, pharmacological, and gene disruption approaches, we demonstrate that proteinase-activated receptor-2 (PAR-2) plays a pivotal role in mediating chronic inflammation. Using an adjuvant monoarthritis model of chronic inflammation, joint swelling was substantially inhibited in PAR-2...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Ferrell, William R., Lockhart, John C., Kelso, Elizabeth B., Dunning, Lynette, Plevin, Robin, Meek, Stephen E., Smith, Andrew J.H., Hunter, Gary D., McLean, John S., McGarry, Frances, Ramage, Robert, Jiang, Lu, Kanke, Toru, Kawagoe, Junichi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2003
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC151840/
https://ncbi.nlm.nih.gov/pubmed/12511586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316913
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares