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The role of intracellular Ca(2+) in the regulation of proteinase-activated receptor-2 mediated nuclear factor kappa B signalling in keratinocytes

1. In this study, we examined the role of Ca(2+) in linking proteinase-activated receptor-2 (PAR2) to the nuclear factor kappa B (NFκB) pathway in a skin epithelial cell line NCTC2544 stably expressing PAR2 (clone G). 2. In clone G, PAR2-mediated NFκB luciferase reporter activity and NFκB DNA-bindin...

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Detalhes bibliográficos
Main Authors: Macfarlane, Scott R, Sloss, Callum M, Cameron, Pamela, Kanke, Toru, McKenzie, Roderick C, Plevin, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576156/
https://ncbi.nlm.nih.gov/pubmed/15821758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706204
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