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Human artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences

A human artificial chromosome (HAC) vector was constructed from a 1-Mb yeast artificial chromosome (YAC) that was selected based on its size from among several YACs identified by screening a randomly chosen subset of the Centre d’Étude du Polymorphisme Humain (CEPH) (Paris) YAC library with a degene...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Henning, Karla A., Novotny, Elizabeth A., Compton, Sheila T., Guan, Xin-Yuan, Liu, Pu P., Ashlock, Melissa A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15181/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9892678/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.2.592
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