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Human artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences

A human artificial chromosome (HAC) vector was constructed from a 1-Mb yeast artificial chromosome (YAC) that was selected based on its size from among several YACs identified by screening a randomly chosen subset of the Centre d’Étude du Polymorphisme Humain (CEPH) (Paris) YAC library with a degene...

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Detalhes bibliográficos
Main Authors: Henning, Karla A., Novotny, Elizabeth A., Compton, Sheila T., Guan, Xin-Yuan, Liu, Pu P., Ashlock, Melissa A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15181/
https://ncbi.nlm.nih.gov/pubmed/9892678
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