Population Pharmacokinetic Analysis of Nonlinear Behavior of Piperacillin during Intermittent or Continuous Infusion in Patients with Cystic Fibrosis

The purpose of this study was to describe the nonlinear pharmacokinetics of piperacillin observed during intermittent infusion and continuous infusion by using a nonparametric population modeling approach. Data were 120 serum piperacillin concentration measurements from eight adult cystic fibrosis (...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Vinks, Alexander A., den Hollander, Jan G., Overbeek, Shelley E., Jelliffe, Roger W., Mouton, Johan W.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2003
Materias:	Pharmacology
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151777/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12543656/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.2.541-547.2003
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