Population Pharmacokinetic Analysis of Nonlinear Behavior of Piperacillin during Intermittent or Continuous Infusion in Patients with Cystic Fibrosis

The purpose of this study was to describe the nonlinear pharmacokinetics of piperacillin observed during intermittent infusion and continuous infusion by using a nonparametric population modeling approach. Data were 120 serum piperacillin concentration measurements from eight adult cystic fibrosis (...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Vinks, Alexander A., den Hollander, Jan G., Overbeek, Shelley E., Jelliffe, Roger W., Mouton, Johan W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Pharmacology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151777/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12543656/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.2.541-547.2003
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