Loss of Caveolin-1 Gene Expression Accelerates the Development of Dysplastic Mammary Lesions in Tumor-Prone Transgenic Mice

Caveolin-1 is the principal structural component of caveolae microdomains, which represent a subcompartment of the plasma membrane. Several independent lines of evidence support the notion that caveolin-1 functions as a suppressor of cell transformation. For example, the human CAV-1 gene maps to a s...

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Main Authors: Williams, Terence M., Cheung, Michelle W.-C., Park, David S., Razani, Babak, Cohen, Alex W., Muller, William J., Di Vizio, Dolores, Chopra, Neeru G., Pestell, Richard G., Lisanti, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151577/
https://ncbi.nlm.nih.gov/pubmed/12631721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-08-0503
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