Caveolin-1-deficient Mice Show Accelerated Mammary Gland Development During Pregnancy, Premature Lactation, and Hyperactivation of the Jak-2/STAT5a Signaling Cascade

It is well established that mammary gland development and lactation are tightly controlled by prolactin signaling. Binding of prolactin to its cognate receptor (Prl-R) leads to activation of the Jak-2 tyrosine kinase and the recruitment/tyrosine phosphorylation of STAT5a. However, the mechanisms for...

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Main Authors: Park, David S., Lee, Hyangkyu, Frank, Philippe G., Razani, Babak, Nguyen, Andrew V., Parlow, Albert F., Russell, Robert G., Hulit, James, Pestell, Richard G., Lisanti, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2002
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129955/
https://ncbi.nlm.nih.gov/pubmed/12388746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.02-05-0071
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