Extensive Loss of Heterozygosity Is Suppressed during Homologous Repair of Chromosomal Breaks
Loss of heterozygosity (LOH) is a common genetic alteration in tumors and often extends several megabases to encompass multiple genetic loci or even whole chromosome arms. Based on marker and karyotype analysis of tumor samples, a significant fraction of LOH events appears to arise from mitotic reco...
Guardat en:
| Publicat a: | Mol Cell Biol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151548/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12509470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.2.733-743.2003 |
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