Llwytho...

mdm2 Is Critical for Inhibition of p53 during Lymphopoiesis and the Response to Ionizing Irradiation

The function of the p53 tumor suppressor protein must be highly regulated because p53 can cause cell death and prevent tumorigenesis. In cultured cells, the p90(MDM2) protein blocks the transcriptional activation domain of p53 and also stimulates the degradation of p53. Here we provide the first con...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mendrysa, Susan M., McElwee, Matthew K., Michalowski, Jennifer, O'Leary, Kathleen A., Young, Karen M., Perry, Mary Ellen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC151546/
https://ncbi.nlm.nih.gov/pubmed/12509446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.2.462-473.2003
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