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Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition
The highly homologous Rnf2 (Ring1b) and Ring1 (Ring1a) proteins were identified as in vivo interactors of the Polycomb Group (PcG) protein Bmi1. Functional ablation of Rnf2 results in gastrulation arrest, in contrast to relatively mild phenotypes in most other PcG gene null mutants belonging to the...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The National Academy of Sciences
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151364/ https://ncbi.nlm.nih.gov/pubmed/12589020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0434312100 |
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