Ubiquitin E3 Ligase Ring1b/Rnf2 of Polycomb Repressive Complex 1 Contributes to Stable Maintenance of Mouse Embryonic Stem Cells

BACKGROUND: Polycomb repressive complex 1 (PRC1) core member Ring1b/Rnf2, with ubiquitin E3 ligase activity towards histone H2A at lysine 119, is essential for early embryogenesis. To obtain more insight into the role of Ring1b in early development, we studied its function in mouse embryonic stem (E...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: van der Stoop, Petra, Boutsma, Erwin A., Hulsman, Danielle, Noback, Sonja, Heimerikx, Mike, Kerkhoven, Ron M., Voncken, J. Willem, Wessels, Lodewyk F. A., van Lohuizen, Maarten
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375055/
https://ncbi.nlm.nih.gov/pubmed/18493325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002235
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki