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Structure and E3-ligase activity of the Ring–Ring complex of Polycomb proteins Bmi1 and Ring1b

Polycomb group proteins Ring1b and Bmi1 (B-cell-specific Moloney murine leukaemia virus integration site 1) are critical components of the chromatin modulating PRC1 complex. Histone H2A ubiquitination by the PRC1 complex strongly depends on the Ring1b protein. Here we show that the E3-ligase activit...

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Detalhes bibliográficos
Main Authors: Buchwald, Gretel, van der Stoop, Petra, Weichenrieder, Oliver, Perrakis, Anastassis, van Lohuizen, Maarten, Sixma, Titia K
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1478191/
https://ncbi.nlm.nih.gov/pubmed/16710298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601144
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