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Structure and E3-ligase activity of the Ring–Ring complex of Polycomb proteins Bmi1 and Ring1b
Polycomb group proteins Ring1b and Bmi1 (B-cell-specific Moloney murine leukaemia virus integration site 1) are critical components of the chromatin modulating PRC1 complex. Histone H2A ubiquitination by the PRC1 complex strongly depends on the Ring1b protein. Here we show that the E3-ligase activit...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1478191/ https://ncbi.nlm.nih.gov/pubmed/16710298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601144 |
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