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Probing the kinesin reaction cycle with a 2D optical force clamp
With every step it takes, the kinesin motor undergoes a mechanochemical reaction cycle that includes the hydrolysis of one ATP molecule, ADP/P(i) release, plus an unknown number of additional transitions. Kinesin velocity depends on both the magnitude and the direction of the applied load. Using spe...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151344/ https://ncbi.nlm.nih.gov/pubmed/12591957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0436709100 |
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