Probing the kinesin reaction cycle with a 2D optical force clamp
With every step it takes, the kinesin motor undergoes a mechanochemical reaction cycle that includes the hydrolysis of one ATP molecule, ADP/P(i) release, plus an unknown number of additional transitions. Kinesin velocity depends on both the magnitude and the direction of the applied load. Using spe...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151344/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12591957/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0436709100 |
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