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Probing the kinesin reaction cycle with a 2D optical force clamp

With every step it takes, the kinesin motor undergoes a mechanochemical reaction cycle that includes the hydrolysis of one ATP molecule, ADP/P(i) release, plus an unknown number of additional transitions. Kinesin velocity depends on both the magnitude and the direction of the applied load. Using spe...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Block, Steven M., Asbury, Charles L., Shaevitz, Joshua W., Lang, Matthew J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151344/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12591957/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0436709100
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